Second Dose H1N1 Vaccine Causes Fever, other side effects

Another reminder on the problems with H1N1 vaccines

LONDON – The European Medicines Agency warns that young children given GlaxoSmithKline's swine flu shot may get a fever after their second dose.

In a statement issued Friday, the European drug regulator said data from GlaxoSmithKline PLC showed a higher number of children aged six months to 3 years had a fever after their second dose of the Pandemrix vaccine, compared with the first. Kids were also more likely to have side effects like muscle pain, drowsiness, and irritability.

The European regulator recommends children get two doses of swine flu vaccine, though Glaxo says one dose is enough.

Glaxo's vaccine contains an adjuvant, a chemical compound to boost the immune response. It is sold across Europe and Canada.
Another formulation of Glaxo's vaccine, without the adjuvant, is available in the U.S. Vaccines with adjuvants usually cause more side effects. No flu vaccines with adjuvants are licensed in the U.S.

Last month, Glaxo advised health authorities not to use one batch of its Canadian-manufactured swine flu vaccine in case it triggered life-threatening side effects like anaphylactic shock.

In a press briefing on Thursday, the World Health Organization's flu chief Keiji Fukuda said that more than 150 million doses of swine flu vaccine have been distributed in more than 40 countries and that they had not seen any evidence to suggest the vaccines caused worrying side effects.

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Posted in: children and flu vaccine,flu vaccine damage,H1N1,H1N1 vaccine harm

Woman Gets 'Kennel Cough' From Her Dog's Vaccine

Bordetella pneumonia in a person from dog vaccine - REMEMBER the "swine flu" nasnal vaccine makes you contagious for 21 days

By Scott Weese
12-4-9

An article in an upcoming edition of Transplant Infectious Disease (>Gisel et al) describes a case of Bordetella bronchiseptica pneumonia in a person who had received a kidney and pancreas transplant. This person had to board her dogs at a veterinary clinic while she was hospitalized for a bowel obstruction that occurred after surgery. The clinic required her dogs to be vaccinated against Bordetella bronchiseptica, a cause of canine "kennel cough." They were vaccinated intranasally (i.e. up the nose) with a modified live vaccine comprised of live B. bronchiseptica that is modified so it is unlikely to cause disease but can still induce a good immune response.

The owner developed pneumonia after returning home and B. bronchiseptica was isolated. Specific testing was not performed to confirm that the vaccine strain caused disease, so it's possible that she was infected by the normal (i.e. "wild type") B. bronchiseptica (which still would have presumably come from the dogs). Immunosuppressed individuals are at high risk for infection by microorganisms that usually don't cause disease in otherwise healthy people. Bordetella bronchisepticais a good example of this. Care should be taken around pets by anyone whose immune system is compromised.

Here are some recommendations pertaining to kennel cough vaccination:

Immunosuppressed individuals should not receive modified live vaccines themselves, and it is probably prudent to extend this recommendation to avoid modified live vaccination of their pets with vaccines like the Bordetella (kennel cough) vaccine.

If vaccination for kennel cough is required for entering a kennel or vet clinic, an exemption should be sought because of the potential risk to the immunocompromised person.

If vaccination must be performed, injectable vaccination is preferred. It doesn't produce as good immunity in the dog compared with intranasal vaccination but the risks to the immunocompromised owner would be much less.
If intranasal vaccination with modified live kennel cough vaccine is used, immunocompromised owners should not be in the same room during vaccination. They should avoid contact with the dog's mouth, nose and face for at least a few days after vaccination and should wash their hands (or use a hand sanitizer) regularly after contact with the dog.

If respiratory disease develops in someone exposed to a dog recently vaccinated against kennel cough, the potential for vaccine-associated disease should be mentioned to the physician.

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Posted in: bordetella,dog vaccine infects human,kennel cough,live vaccine